Lymph Node Evolution in Eyelid and Orbit Squamous Cell Carcinomas
LARYNGOSCOPE(2024)
摘要
ObjectivesTo describe a large cohort of eyelid and periorbital SCCs, to compare the location of the tumor and of the pathological lymph nodes, and to analyze the risk factors for lymph node involvement among tumor characteristics.MethodsAll patients managed inside our institution for an eyelid and periorbital SCCs were included. Tumor characteristics, imaging setup, excision margins, lymph node evolution features, local, regional, and distant recurrences rates, and global survival were reported. The risk for lymph node involvement and location of pathological lymph nodes were analyzed through univariate and multivariate analyses.ResultsBetween January 2012 and August 2022, 115 patients were included, and 18 presented a lymph node evolution (15.7%), involving the parotid gland in 16 cases (88.9%), the submental and submandibular areas in seven cases (38%), and the jugular and carotid areas in four cases (22%). Tumor size above 20 mm, infiltration of the external canthus and periorbital structures, the presence of perineural invasion or vascular embolism, the depth of infiltration, and the presence of a local recurrence were significantly associated with the risk of lymph node evolution.ConclusionPeriorbital and eyelid SCCs present a true potential for lymph node evolution especially through the parotid gland. Extension setup including the parotid gland and neck should be mandatory, and lymph node dissection should be associated in case of parotidectomy for lymph node involvement.Level of EvidenceIV Laryngoscope, 2024 This article summarizes our findings regarding lymph node evolution inside the parotid gland and submental and submanidbular nodes. We recommend to perform systematically an imaging setup and to perform an extensive neck dissection involving IA (submental areas) et IB (submandibular areas) areas when facing a lymph node evolution. Parotidectomy should be proposed only if pathological. image
更多查看译文
关键词
eyelid,lymph nodes,orbit,parotid gland,squamous cell carcinomas
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要