1413P Antibiotic Administration and Outcome of Patients with Advanced Gastric Cancer Receiving Programmed Death-1 Inhibitors or with Single-Agent Chemotherapy

Minkyu Jung,C.G. Kim,SJ Shin,Min Hee Hong,Hyun Cheol Chung,Sun Young Rha, H.S. Kim,CK Lee,J.H. Lee,Young Mi Han,H. Kim,J.H. Kim, S.Y. Lee, H. Jeung

Annals of oncology（2021）

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摘要

Antibiotic therapy disrupts microbiota homeostasis, which is suggested to impair response to immune checkpoint blockade. We assessed whether antibiotic treatment predicts treatment outcomes of programmed death-1 (PD-1) inhibitors or chemotherapy in advanced gastric cancer (AGC).

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