Fentanyl and Xylazine Crisis: Crafting Coherent Strategies for Opioid Overdose Prevention.

Lakshit Jain, Jasleen Kaur,Shahana Ayub, Danya Ansari,Rizwan Ahmed, Abdul Qadir Dada,Saeed Ahmed

World Journal of Psychiatry（2024）

Cited 0|Views1

Abstract

The United States is in the throes of a severe opioid overdose epidemic, primarily fueled by the pervasive use of fentanyl and the emerging threat of xylazine, a veterinary sedative often mixed with fentanyl. The high potency and long duration of fentanyl is compounded by the added risks from xylazine, heightening the lethal danger faced by opioid users. Measures such as enhanced surveillance, public awareness campaigns, and the distribution of fentanyl-xylazine test kits, and naloxone have been undertaken to mitigate this crisis. Fentanyl-related overdose deaths persist despite these efforts, partly due to inconsistent policies across states and resistance towards adopting harm reduction strategies. A multifaceted approach is imperative in effectively combating the opioid overdose epidemic. This approach should include expansion of treatment access, broadening the availability of medications for opioid use disorder, implementation of harm reduction strategies, and enaction of legislative reforms and diminishing stigma associated with opioid use disorder.

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Key words

Fentanyl,Xylazine,Opioid overdose,Epidemic,Opioid use disorder,Buprenorphine,Medications for opioid use disorder

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Pretraining has recently greatly promoted the development of natural language processing (NLP)
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【要点】：论文针对美国当前由芬太尼和赛拉嗪引发的鸦片类药物过量危机，提出了一个全面策略，旨在预防鸦片类药物过量，包括扩大治疗获取、增加药物可用性、实施减害策略以及立法改革和减少鸦片类药物使用污名。

【方法】：作者通过分析当前鸦片类药物过量问题的现状，评估了已有干预措施的有效性，并提出了一个多维度的综合策略。

【实验】：论文未涉及具体的实验研究，未提及使用的数据集名称，因此无法概括实验及数据集名称和结果。