Synthesis and Biological Characterization of an Orally Bioavailable Lactate Dehydrogenase-A Inhibitor Against Pancreatic Cancer

Horrick Sharma,Somrita Mondal, Uzziah Urquiza, Colter Esparza, Seth Bartlett, Landon Santa -Pinter, Hanna Hill, Madalyn White, Pragya Sharma,Lerin Luckett-Chastain,Anne Cooper, Mohammad Rasel,Philip Gao,Kevin P. Battaile, Surendra K. Shukla,Scott Lovell,Michael A. Ihnat

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

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Lactate Dehydrogenase-A,Pancreatic cancer,Small molecule inhibitor,Lactate,Pharmacokinetics,OXPHOS

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