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Prediction of the Liver Safety Profile of a First-in-class Myeloperoxidase Inhibitor Using Quantitative Systems Toxicology Modeling.

Jeffrey L. Woodhead, Yeshi Gebremichael, Joyce Macwan, Irfan A. Qureshi,Richard Bertz,Victoria Wirtz,Brett A. Howell

XENOBIOTICA(2024)

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Key words
Drug-induced liver injury,quantitative systems toxicology,quantitative systems pharmacology,biological modeling,verdiperstat,predictive toxicology,drug safety
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