Automated Volumetry of Amygdala Subregions in Parkinson’s Disease Patients

Cognitive impairment is very common in patients with Parkinson’s disease (PD). The amygdala in the limbic system of midbrain has been proved to play a unique role in cognitive function. However, there are almost no studies on changes in amygdala structure, especially the volume of amygdala subregions, in PD patients. In this study, automated volumetry of amygdala subregions in PD patients was performed and compared with healthy controls, and found that PD patients have amygdala subregions atrophy, especially in bilateral accessory basal nucleus, bilateral cortical nucleus and right medial nucleus.