Supplemental Figures 2 to 4 from Retention of Interstitial Genes between TMPRSS2 and ERG Is Associated with Low-Risk Prostate Cancer

Supplemental Figure 2 presents genome coverage plots for four example cases illustrating complex rearrangements between chromosomes (A-D) plus a schematic of the complex TMPRSS2-ERG rearrangement in PR084. Supplemental Figure 3 illustrates the number of breakpoints from genomic rearrangements hitting chromosome 21q. Supplemental Figure 4 illustrates survival analysis from data from Fraser et al 2017 comparing non-indolent prostate cancers with TMPRSS2-ERG fusions with interstitial deletion or retention.