Supplement Figure 1 from Auranofin Enhances Ibrutinib's Anticancer Activity in EGFR-Mutant Lung Adenocarcinoma

Dose-response curves of acalabrutinib in four NSCLC cell lines. H1975 and HCC827 cells are EGFR mutant while Calu3 and A549 are EGFR wild-type. Data are presented as the mean {plus minus} standard deviation (SD) of a quadruplet assay. Cells treated with DMSO alone were used as controls, and their values were set as 1. All four cell lines have IC50 > 3 μM for acalabrutinib.