A Drug–drug Interaction Study and Physiologically Based Pharmacokinetic Modelling to Assess the Effect of an Oral 5‐lipoxygenase Activating Protein Inhibitor on the Pharmacokinetics of Oral Midazolam

Jane Knochel, Vijender Panduga,Karin Nelander,Maria Heijer,Eva-Lotte Lindstedt, Hodan Ali,Malin Aurell, Helena Odesjo,Pablo Forte, Kat Connolly,Hans Ericsson,Iain Macphee

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY（2024）

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关键词
5-lipoxygenase activating protein inhibitor,drug-drug interaction,healthy subjects,midazolam,PBPK,pharmacokinetics
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