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Effective dosage and mode of exercise for enhancing cognitive function in Alzheimer's disease and dementia: a systematic review and Bayesian Model-Based Network Meta-analysis of RCTs

Yuan Yuan, Yong Yang, XiaoFei Hu,Lin Zhang, Zhiyu Xiong, Ying Bai, JiaLe Zeng, Feng Xu

BMC Geriatrics(2024)

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摘要
Research the dose–response relationship between overall and certain types of exercise and cognitive function in older adults with Alzheimer's disease and dementia. Systemic and Bayesian Model-Based Network Meta-Analysis. In our study, we analyzed data from randomized controlled trials investigating the effects of different exercises on cognitive outcomes in older adults with AD. We searched the Web of Science, PubMed, Cochrane Central Register of Controlled Trials, and Embase up to November 2023. Using the Cochrane Risk of Bias tool (Rob2) for quality assessment and R software with the MBNMA package for data analysis, we determined standard mean differences (SMDs) and 95
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关键词
Old adults,Alzheimer,Dementia,Exercise,Dose–response,RCTs,Network meta-analysis
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