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Mapping in Silico Genetic Networks of the KMT2D Tumour Suppressor Gene to Uncover Novel Functional Associations and Cancer Cell Vulnerabilities

Yuka Takemon,Erin D. Pleasance,Alessia Gagliardi,Christopher S. Hughes,Veronika Csizmok,Kathleen Wee,Diane L. Trinh,Ryan D. Huff,Andrew J. Mungall,Richard A. Moore,Eric Chuah,Karen L. Mungall, Eleanor Lewis,Jessica Nelson,Howard J. Lim,Daniel J. Renouf,Steven JM. Jones,Janessa Laskin,Marco A. Marra

Genome medicine（2024）

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关键词
Tumour suppressor genes,KMT2D,Genetic networks,Synthetic lethality,WRN inhibitors
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