High Affinity Inhibitors of the Macrophage Infectivity Potentiator Protein from Trypanosoma Cruzi, Burkholderia Pseudomallei, and Legionella Pneumophila─a Comparison

Theresa Lohr,Carina Herbst,Nicole M. Bzdyl,Christopher Jenkins,Nicolas J. Scheuplein,Wisely Oki Sugiarto,Jacob J. Whittaker,Albert Guskov,Isobel Norville,Ute A. Hellmich,Felix Hausch,Mitali Sarkar-Tyson,Christoph Sotriffer,Ulrike Holzgrabe

ACS INFECTIOUS DISEASES（2024）

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Key words

macrophage infectivity potentiator protein,fluorescencepolarization assay,FKBP, halogen bond,structure-activityrelationship,quantum mechanical calculations

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