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Physiologically-based Pharmacokinetic Modeling to Predict the Exposure and Provide Dosage Regimens of Ustekinumab in Pediatric Patients with Inflammatory Bowel Disease

Xiaoxi Cai,Wanhong Wu,Guimu Guo,Jiarui Chen,Jianwen Xu,Weiwei Lin,Pinfang Huang,Cuihong Lin,Rongfang Lin

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES（2024）

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关键词
PBPK model,Ustekinumab,Inflammatory bowel disease,Pediatric patients,Individualized administration
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