Transcriptomic and Spatial Dissection of Human Ex Vivo Right Atrial Tissue Reveals Proinflammatory Microvascular Changes in Ischemic Heart Disease

Suvi Linna-Kuosmanen,Eloi Schmauch,Kyriakitsa Galani, Johannes Ojanen,Carles A. Boix,Tiit Ord,Anu Toropainen,Prosanta K. Singha,Pierre R. Moreau, Kristiina Harju,Adriana Blazeski,Asa Segerstolpe, Veikko Lahtinen,Lei Hou, Kai Kang, Elamaran Meibalan,Leandro Z. Agudelo,Hannu Kokki,Jari Halonen,Juho Jalkanen,Jarmo Gunn,Calum A. Macrae, Maija Hollmen, Juha E. K. Hartikainen, Minna U. Kaikkonen, Guillermo Garcia-Cardena, Pasi Tavi, Tuomas Kiviniemi,Manolis Kellis

CELL REPORTS MEDICINE(2024)

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关键词
single cell,transcriptomics,spatial transcriptomics,cardiovascular disease,heart,ischemic heart disease,heart failure,disease mechanism,inflammation,genetic variation
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