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Introduction of Sugar-Modified Nucleotides into CpG-containing Antisense Oligonucleotides Inhibits TLR9 Activation

Tokuyuki Yoshida, Tomoko Hagihara,Yasunori Uchida,Yoshiyuki Horiuchi,Kiyomi Sasaki,Takenori Yamamoto,Takuma Yamashita,Yukihiro Goda,Yoshiro Saito,Takao Yamaguchi,Satoshi Obika,Seiji Yamamoto,Takao Inoue

SCIENTIFIC REPORTS（2024）

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Key words
Antisense oligonucleotides,Sugar-modified nucleotides,Innate immunity,Toll-like receptors
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