Chrome Extension
WeChat Mini Program
Use on ChatGLM
VIPCreated with Sketch.

    • Decentralized Colorectal Cancer Care: Benefit or Burden in the Pandemic? – an International Comparative Study in Two Health Care Systems (DCCC Study)

    B. Wiesler,J. M. Gass, J. Metzger, M. Hartel,C. Nebiker,U. Zingg, D. Stimpfle,C. T. Viehl, A. Mueller,M. Worni,P. Studer, L. Eisner, C. Andreou, R. Rosenberg,R. Galli, B. P. Mueller,K. Denhaerynck,P. Hall, C. Gallagher,C. Lilley, M. Zuber,H. M. Paterson,M. von Strauss Und Torney

    BRITISH JOURNAL OF SURGERY（2024）

    Clarunis Univ | Cantonal Hosp Lucerne | Cantonal Hosp Aarau | Spital Limmattal | Spitalzentrum Biel | Swiss Inst Translat & Entrepreneurial Med | Cantonal Hosp Olten | Cantonal Hosp Basel Land | Univ Basel | Univ Edinburgh | Western Gen Hosp Edinburgh

    Cited 0|Views10
    Abstract
    Abstract Background Beneficial effects of centralization could be shown. During SARS-CoV2 pandemic however, the centralization in the UK healthcare system led to cessation of screening colonoscopies and oncological resections. In the decentralized healthcare system of Switzerland, a high frequency of colonoscopies could be maintained. Aims The aim of this international study is to evaluate if a decentralized health care systems can prevent the threatening unmet needs of colorectal cancer patients under pandemic conditions. Methods This observational trial was performed in the south-east of Scotland and in the extended northwest of Switzerland with a catchment area of 1.5 Mio. inhabitants each. Patients with colorectal cancer diagnosed during January 2019 and December 2022 were included. Results Six thousand six hundred and eighty patients were included in this preliminary analysis (4059 in the NHS group and 2621 in the Swiss group). In Scotland the median number of diagnosed patients per quarter was 258 pre-pandemics, 218 during lockdown and 258 after lockdown (p=0.56). There was no significant alteration of the median diagnosed patients per quarter during different phases in Switzerland (165 pre-pandemic vs. 187 during lockdown vs. 162 post-lockdown, p=0.56). In Scotland the median number of all performed tumor treatments per quarter were lower during lockdown (83 pre-pandemic vs. 75 during lockdown vs. 93 post-lockdown, p<0.01). In Switzerland the median treatment numbers per quarter didn´t differ during different phases (56 pre-pandemic vs. 62 during lockdown vs. 60 post-lockdown, p=0.51). The number of patients diagnosed with a T4 tumor during pandemic was higher in Scotland than in Switzerland (28% vs. 19%, p<0.01). The 30-day mortality under pandemic condition was 7.5% (65 of 859) in Scotland compared to 3.7% (14 of 374) in Switzerland (p=0.01). Conclusion SARS-CoV2 pandemic led to a reduction in performed cancer treatments in Scotland. In Switzerland's decentralized healthcare system, cancer treatments were maintained during pandemic.
    More
    Translated text
    求助PDF
    上传PDF
    View via Publisher
    Bibtex
    AI Read Science
    AI Summary
    AI Summary is the key point extracted automatically understanding the full text of the paper, including the background, methods, results, conclusions, icons and other key content, so that you can get the outline of the paper at a glance.
    Example
    Background
    Key content
    Introduction
    Methods
    Results
    Related work
    Fund
    Key content
    • Pretraining has recently greatly promoted the development of natural language processing (NLP)
    • We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performance
    • We propose a method called M6 that is able to process information of multiple modalities and perform both single-modal and cross-modal understanding and generation
    • The model is scaled to large model with 10 billion parameters with sophisticated deployment, and the 10 -parameter M6-large is the largest pretrained model in Chinese
    • Experimental results show that our proposed M6 outperforms the baseline in a number of downstream tasks concerning both single modality and multiple modalities We will continue the pretraining of extremely large models by increasing data to explore the limit of its performance
    Upload PDF to Generate Summary
    Must-Reading Tree
    Example
    Generate MRT to find the research sequence of this paper
    Data Disclaimer
    The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn
    Chat Paper
    【要点】：该研究通过国际比较分析，探讨了在SARS-CoV2大流行期间， decentralized（分散式）的结直肠癌治疗模式是否能避免患者未满足的需求，并发现分散式医疗系统在疫情期间保持了较高的治疗数量和质量。
    

    【方法】：研究采用观察性试验方法，在苏格兰东南部和瑞士西北部各选取150万居民的覆盖区域，对2019年1月至2022年12月期间诊断为结直肠癌的患者进行数据收集和分析。
    

    【实验】：共纳入6680名患者（苏格兰国家健康服务体系组4059名，瑞士组2621名）。结果显示，苏格兰在疫情封锁期间每季度诊断的患者数量和肿瘤治疗数量均有所下降，而瑞士在各个阶段诊断和治疗数量保持稳定。苏格兰疫情期间T4期肿瘤的诊断率高于瑞士，且30天死亡率也较高。