A G-quadruplex-binding Platinum Complex Induces Cancer Mitochondrial Dysfunction Through Dual-Targeting Mitochondrial and Nuclear G4 Enriched Genome

Keli Kuang,Chunyan Li,Fatlinda Maksut,Deepanjan Ghosh,Robin Vinck,Maolin Wang,Joël Poupon,Run Xiang,Wen Li,Fei Li,Zhu Wang,Junrong Du,Marie-Paule Teulade-Fichou,Gilles Gasser,Sophie Bombard,Tao Jia

JOURNAL OF BIOMEDICAL SCIENCE（2024）

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Key words
G4,Mitochondrial genome,Mito-Nuclear interactions,ROS,Platinum complex,Chemotherapy
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