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Design and Synthesis of Novel JNK Inhibitors Targeting Liver Pyruvate Kinase for the Treatment of Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma

Shazia Iqbal,Jihad Sebhaoui,Sajda Ashraf,Mehmet Ozcan,Woonghee Kim, Burcu Belmen, Guldeniz Yesilyurt, Essam Hanashalshahaby,Cheng Zhang,Mathias Uhlen,Jan Boren,Hasan Turkez,Adil Mardinoglu

BIOORGANIC CHEMISTRY（2024）

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关键词
Liver pyruvate kinase,JNK-IN-5A,HCC,NAFLD,TAG level
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