421. Associated Impairments in Neurocognition and Psychophysiological Biomarkers for Psychosis Risk in Individuals with 22q11.2 Deletion Syndrome

22q11DS is a robust genetic predictor of schizophrenia (SCZ) and other psychiatric illnesses: nearly 30% of individuals develop SCZ. Understanding the relationship of cognition and psychophysiological variables could lead to a greater understanding of circuit-based abnormal functioning in 22q11DS and SCZ.