Comparison of anterior segment parameters of patients with myopia measured using 2 swept-source optical coherent biometry devices

Abstract Background This study assessed the agreement of anterior segment parameters of patients with myopia measured using 2 swept-source optical coherent biometry devices: the Colombo intraocular lens (IOL) and IOL Master 700. Methods Eighty patients (male/female, 22/58; average age, 29.11 ± 7.77 years) with myopia (159 eyes) were included in this study in May 2023. All participants underwent measurements using the IOL Master 700 and Colombo IOL to obtain axial length (AXL), central corneal thickness (CCT), lens thickness (LT), white-to-white (WTW), and front flat (K1) and steep (K2) corneal keratometry. The measurements by the 2 devices were compared using the generalized estimating equation, correlation analysis, and Bland-Altman plots. Results The Colombo IOL measured larger values for WTW (OR = 1.277, p < 0.0001) and lower values for K2 (OR = 0.587, p < 0.033). All anterior segment measurements by both instruments showed positive correlations (0.8079 < r < 0.9996, p < 0.01), with AXL demonstrating the strongest correlation (r = 0.9996, p < 0.0001). The intraclass correlation coefficients for AXLs measured by both instruments was 0.999 (p < 0.0001), and Bland-Altman plot indicated that the 95% limits of agreement ranged from − 0.078 to 0.11. The measurement deviations of K2, LT, WTW between IOL Master 700 and Colombo IOL were 0.526 D, -0.085 mm and − 0.244 mm, respectively. Conclusions The Colombo IOL and IOL Master 700 comparably measured CCT and AXL. However, their measurements of corneal refractive power, WTW and LT were significantly different, necessitating caution in using two devices interchangeably in clinical practice.