Covalent modulation of mPGES1 activity via α,β-unsaturated aldehyde group: Implications for downregulating PGE2 expression and antipyretic response

Fuyun Chi,Man Zhang,Yiman Han,Fukui Shen, Shijie Peng, Bo Su,Yuanyuan Hou,Gang Bai

Chinese Chemical Letters(2024)

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关键词
α,β-Unsaturated aldehyde,Covalent binding,mPGES1,PGE2,Antipyretic
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