0295 Influence of Sleep Regularity, Chronotype, and Sleep Duration on Daytime Sleepiness Caused by Sleep Disorders

Abstract Introduction Excessive daytime sleepiness is characterized by the difficulty of staying awake during daytime. The goal of this research is to examine the role of regularity, sleep duration, and chronotype on the association between sleep disorders and daytime sleepiness. To do this, we leveraged the Sleep Number platform to acquire longitudinal objective sleep with survey data from a single point in time. Methods An IRB-approved survey, which included questions about diagnosed sleep disorders and daytime sleepiness, was presented to a cohort of Sleep Number customers in the June 12 to 26, 2023 period. Objective data including sleep duration, bedtime, restful sleep duration, mean breathing rate, and heart rate collected between May 1 and June 30, 2023 were used along with survey responses. Individual sleep regularity and chronotype were quantified using objective data. Regularity was categorized into regular or irregular if bedtime variability was lower or greater than 60 minutes. Chronotype was categorized into early, intermediate, or late if mean sleep onset time was before 10 pm, between 10 and 11:59 pm, or after 12 am. Odd-ratios (OR) were used to quantify the influence of regularity, chronotype, and sleep duration on daytime sleepiness moderated by sleep disorders. Results The responder count was 22,082 (9530M/12479F). Men were 56.6 (SD 13.9) and Women 54.9 (SD 13.8) years-old on average. Daytime sleepiness was significantly associated with the presence of untreated sleep disorders (insomnia, apnea, and RLS). Individuals being treated for apnea and insomnia demonstrated significantly less daytime sleepiness. Healthy individuals showed a significant association between early chronotype and longer sleep duration with reduced daytime sleepiness. Individuals with apnea who receive treatment showed a significant association between longer sleep and reduced daytime sleepiness. In the case of insomnia, regularity, chronotype or sleep duration do not moderate any significant relationship with daytime sleepiness. For RLS longer sleep duration leads to lower daytime sleepiness. Conclusion Daytime sleepiness is significantly associated with any untreated sleep disorders. Regularity, chronotype and sleep duration had limited influence on daytime sleepiness caused by sleep disorders. Healthy individuals had lower daytime sleepiness if they had an earlier chronotype and longer sleep duration. Support (if any)