MP40-19 EVALUATING THE INCIDENCE OF NEPHROLITHIASIS SURGERY BEFORE AND AFTER PARATHYROIDECTOMY: A RETROSPECTIVE OBSERVATIONAL STUDY

You have accessJournal of UrologyStone Disease: Epidemiology & Evaluation I (MP40)1 May 2024MP40-19 EVALUATING THE INCIDENCE OF NEPHROLITHIASIS SURGERY BEFORE AND AFTER PARATHYROIDECTOMY: A RETROSPECTIVE OBSERVATIONAL STUDY Ashley Li, Kelvin Lim, David Song, Angela Wang, Jacob Moalem, Jathin Bandari, Rajat Jain, and Scott Quarrier Ashley LiAshley Li , Kelvin LimKelvin Lim , David SongDavid Song , Angela WangAngela Wang , Jacob MoalemJacob Moalem , Jathin BandariJathin Bandari , Rajat JainRajat Jain , and Scott QuarrierScott Quarrier View All Author Informationhttps://doi.org/10.1097/01.JU.0001008788.18007.3f.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Primary hyperparathyroidism carries an increased kidney stone prevalence of 15-30%. Patients who undergo parathyroidectomy have significantly reduced rates of kidney stone events based on imaging and patient reported history. However, there has been limited knowledge on the impact of parathyroidectomy on stone disease requiring surgical intervention. The aim of this study is to compare the incidence of kidney stone surgery before and after parathyroidectomy. METHODS: We retrospectively reviewed patients>18 years old who underwent parathyroidectomy from 2015 to 2023 at our institution. We evaluated the incidence of kidney stone surgery including shockwave lithotripsy (SWL), ureteroscopy (URS) and percutaneous nephrolithotomy (PCNL) based on CPT codes in this patient population. We performed univariate analysis (Chi-Square Test) to compare the incidence rate before and after parathyroidectomy. RESULTS: We reviewed 2104 patients who underwent parathyroidectomy and identified 367 kidney stone surgeries. Patients were 75% female, 18% non-white race and had a median age of 60 years (IQR 52-70) at the time of parathyroidectomy. The median follow-up time was 4.75 years before and 3.6 years after parathyroidectomy. The incidence of kidney stone surgery in patients pre- vs post- parathyroidectomy was 181/10553 person years (1.7%) vs 75/8189 person years (0.9%) respectively, (p<0.0001). Thus, the incidence rate of requiring stone surgery decreased by 1.87 times following parathyroidectomy (95% CI 1.42-2.48, p<0.0001). The cases of URS and SWL decreased whereas the cases of PCNL increased (Table 1). CONCLUSIONS: In patients with hyperparathyroidism, the incidence of stone disease requiring surgical intervention significantly decreased following parathyroidectomy. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e671 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Ashley Li More articles by this author Kelvin Lim More articles by this author David Song More articles by this author Angela Wang More articles by this author Jacob Moalem More articles by this author Jathin Bandari More articles by this author Rajat Jain More articles by this author Scott Quarrier More articles by this author Expand All Advertisement PDF downloadLoading ...