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Posttranscriptional Regulation of FAN1 by Mir-124-3p at Rs3512 Underlies Onset-Delaying Genetic Modification in Huntington’s Disease

Kyung-Hee Kim,Eun Pyo Hong,Yukyeong Lee,Zachariah L. Mclean, Emanuela Elezi,Ramee Lee,Seung Kwak,Branduff Mcallister,Thomas H. Massey,Sergey Lobanov,Peter Holmans,Michael Orth,Marc Ciosi,Darren G. Monckton,Jeffrey D. Long,Diane Lucente,Vanessa C. Wheeler,Marcy E. Macdonald,James F. Gusella,Jong- Min Lee

Proceedings of the National Academy of Sciences（2024）

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关键词
Huntington's disease,genetic modifier,FAN1,rs3512,miR-124-3p
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