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Bayesian Extension of the Weibull AFT Shared Frailty Model with Generalized Family of Distributions for Enhanced Survival Analysis Using Censored Data

Mohammad Parvej,Athar Ali Khan

Journal of applied statistics(2024)

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摘要
In survival analysis, the Accelerated Failure Time (AFT) shared frailty model is a widely used framework for analyzing time-to-event data while accounting for unobserved heterogeneity among individuals. This paper extends the traditional Weibull AFT shared frailty model using half logistic-G family of distributions (Type I, Type II and Type II exponentiated) through Bayesian methods. This approach offers flexibility in capturing covariate influence and handling heavy-tailed frailty distributions. Bayesian inference with MCMC provides parameter estimates and credible intervals. Simulation studies show improved model predictive performance compared to existing models, and real-world applications demonstrate its practical utility. In summary, our Bayesian Weibull AFT shared frailty model with Type I, Type II and Type II exponentiated half logistic-G family distributions enhances time-to-event data analysis, making it a versatile tool for survival analysis in various fields using STAN in R.
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关键词
Type I half-logistic-G,type II half logistic-G,type II exponentiated half logistic-G,Weibull distribution,AFT,shared-frailty,censored data,LOOIC,WAIC,STAN
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