Myocardial Functional Improvement is Associated with Improved HF-Related Outcomes in Patients While on Durable LVAD: an STS INTERMACS Analysis

Purpose: Chronic HF patients with reduced ejection fraction can experience cardiac structural and functional improvement in response to guideline-directed medical therapy (GDMT) and this has been associated with better outcomes. A subset of advanced HF patients on LVAD support and GDMT can also experience cardiac structural and functional improvement. Using a large multicenter dataset we sought to investigate how the improved cardiac function affected HF-related outcomes while on durable LVAD.