Rescuing Alpha-synuclein Toxicity Through Neuron-specific Enhancement of Autophagy (P7-3.003)
Neurology（2024）
Abstract
To overcome proteostatic barriers and ameliorate Parkinson disease (PD) pathogenesis, we sought to determine whether knockdown of MTMR5 facilitates alpha-synuclein (asyn) turnover and rescues asyn proteotoxicity.
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