A Phenotypic Screening Approach to Target P60amotl2-Expressing Invasive Cancer Cells

Pedro Fonseca,Weiyingqi Cui,Nona Struyf,Le Tong,Ayushi Chaurasiya, Felipe Casagrande,Honglei Zhao, Dinura Fernando,Xinsong Chen,Nicholas P. Tobin,Brinton Seashore-Ludlow,Andreas Lundqvist,Johan Hartman,Anita Göndör,Päivi Östling,Lars Holmgren

Journal of Experimental & Clinical Cancer Research（2024）

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关键词

Cancer,Cancer invasion,Metastasis,Mechanotransduction,Phenotypic drug screening,Patient-derived organoids,AmotL2,p60AmotL2,BET inhibitors,Nascent RNA-seq

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