Hepatoid Adenocarcinoma of the Esophagus with Thyroid Metastasis: A Case Report.

Rare hepatoid adenocarcinomas are highly heterogeneous. In this case, hepatoid adenocarcinoma occurred in both the esophagus and thyroid, and the combination of chemotherapy and immunotherapy may be a promising therapeutic tool for rare tumors. Laryngoscope, 2024 Our innovation lies in a case report that hepatoid adenocarcinoma occurred in the esophagus and thyroid. The clinical manifestations of rare hepatoid adenocarcinoma have a high degree of heterogeneity, that the combination of chemotherapy and immunotherapy may be a promising therapeutic tool for this rare tumor, which contributes to understanding the mechanism of tumor from a comprehensive perspective and the personalized treatment of this rare malignancy. image