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Genome Engineering with Cas9 and AAV Repair Templates Generates Frequent Concatemeric Insertions of Viral Vectors

Fabian P. Suchy,Daiki Karigane,Yusuke Nakauchi,Maimi Higuchi,Jinyu Zhang,Katja Pekrun,Ian Hsu,Amy C. Fan,Toshinobu Nishimura,Carsten T. Charlesworth,Joydeep Bhadury,Toshiya Nishimura,Adam C. Wilkinson,Mark A. Kay,Ravindra Majeti,Hiromitsu Nakauchi

Nature biotechnology（2024）

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关键词
Genome Engineering,Genomic Integration,Gene Editing,Multiplex Genome Editing
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