Probing the Active Site of Class 3 L-asparaginase by Mutagenesis. I. Tinkering with the Zinc Coordination Site of ReAV
FRONTIERS IN CHEMISTRY(2024)
关键词
hydrolase,amidohydrolase,L-asparaginase,leukemia,metalloprotein,site-directed mutagenesis,ITC,X-ray crystallography
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