In Situ Detection of Ablation Area Extension and Local Tumor Necrosis Using Self-Constructed Fiberoptic System

Introduction The maximum effect of the local ablation (radiofrequency and microwave therapy) of liver tumors is achieved when the ablation region completely encloses the tumor area. In the present study, the self-constructed system based on fiberoptic detection of tissue autofluorescence was used for identification of local extension of ablation area and of chemotherapy-induced local tumor necrosis.