The effect of hemodialysis on the ocular anterior morphometry and intraocular pressure

Introduction/Objective This study evaluates the effects of hemodialysis (HD) on intraocular pressure (IOP) and ocular anterior chamber morphometry in end-stage renal disease (ESRD) patients. Methods In total, 32 ESRD patients (50 eyes) who were on regular HD program, underwent ocular examination. To all of them, 30 minutes before HD and 30 minutes after the end of the HD session, central corneal thickness (CCT), keratometric values (K1, K2), axial length (AL), anterior chamber depth (ACD), and lens thickness (LT) were measured using the Lenstar 900 Haag-Streit USA device (Haag-Streit Group, Koniz, Switzerland). IOP was measured using Goldman applanation tonometry. Results IOP before HD was 15.74 ± 3,043 while after HD it was 15.14 ± 3,07 (p = 0.125); K1 and K2 values were 43.11 ± 1.68 vs. 43.13 ± 1.73 (p = 0.688) and 43.11 ± 1.60 vs. 43.11 ± 1.66 (p = 0.158); AL increase from 23.25 ± 0.68 to 23.27 ± 0.68 in postHD (p = 0.158) as well as AL from 23.25 ± 0.68 to 23.27 ± 0.68 (p = 0.264); ACD decrease insignificantly from 3.14 ± 0.40 to 3.10 ± 0.42 (p = 0.063); mean LT before HD was 4.66 ± 0.38 while after HD it was 4.67 ± 0.36 (p = 0.290) and CCT was 563.68 ± 42.02 vs. 563.34 ± 42.26 (p = 0.777). Conclusion HD has no significant influences on ocular anterior segment structures such as on CCT, ACD, LT, AL, K values as well as IOP.