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Design and Optimization of Piperidine-Substituted Thiophene[3,2-D]pyrimidine-based HIV-1 NNRTIs with Improved Drug Resistance and Pharmacokinetic Profiles

Yanying Sun,Zhenzhen Zhou, Zhongling Shi,Fabao Zhao,Minghui Xie,Zongji Zhuo,Erik De Clercq,Christophe Pannecouque,Dongwei Kang,Peng Zhan,Xinyong Liu

ACTA PHARMACEUTICA SINICA B（2024）

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关键词
HIV-1,NNRTIs,NNIBP,Structural alert,Anti-HIV-1 drug candidate
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