Discovery of DNL343: A Potent, Selective, and Brain-Penetrant Eif2b Activator Designed for the Treatment of Neurodegenerative Diseases.
Robert A. Craig II,Javier De Vicente,Anthony A. Estrada,Jianwen A. Feng,Katrina W. Lexa, Mark J. Canet,William E. Dowdle,Rebecca I. Erickson, Brittany N. Flores,Patrick C. G. Haddick,Lesley A. Kane,Joseph W. Lewcock,Nathan J. Moerke,Suresh B. Poda,Zachary Sweeney,Ryan H. Takahashi,Vincent Tong,Jing Wang,Ernie Yulyaningsih,Hilda Solanoy,Kimberly Scearce-Levie,Pascal E. Sanchez, Liwei Tang,Musheng Xu, Rui Zhang,Maksim Osipov JOURNAL OF MEDICINAL CHEMISTRY（2024）
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