Malvidin Mitigates Sepsis-induced Cardiac Injury by Modulating the TLR4-iNOS-COX-2 Inflammatory Pathway and the Bax/Bcl-2/Cyto-C Mitochondrial Apoptosis Pathway in a p38 MAPK-dependent Manner

In critical care medicine, sepsis is a dangerous systemic condition that is highly prevalent and is associated with high morbidity and mortality rates[1]. The high mortality rate associated with sepsis is closely related to multi-organ dysfunction, with heart injury being particularly critical and considered the starting point of multi-organ injury[2].