Discovery of a Novel Thienopyrimidine Compound As a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability.

Xiaoyu Shi,Tong Zhao,Shuo Wang,Shujing Xu,Hui Liao,Shenghua Gao,Zhen Gao,Jian Zhang, Danhui Qi,Zhijiao Zhang,Fengxin Zheng, Youzhao Wang, Zhenqian Wang, Mingyu Yang, Qian Yang,Fan Yi,Jianxin Pang,Xinyong Liu,Peng Zhan

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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Hyperuricemia

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