NEK1 Haploinsufficiency Worsens DNA Damage but Not Defective Ciliogenesis in C9ORF72 Patient-Derived Ipsc-Motoneurons

Serena Santangelo,Sabrina Invernizzi,Marta Nice Sorce,Valeria Casiraghi,Silvia Peverelli,Alberto Brusati,Claudia Colombrita,Nicola Ticozzi,Vincenzo Silani,Patrizia Bossolasco,Antonia Ratti

Human molecular genetics（2024）

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Key words
ALS,C9ORF72,NEK1,iPSC-motoneurons,primary cilium
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