Atypical case of glioblastoma localization: infratentorial localization (Clinical Case and the Review of the Literature)

Glioblastoma is the most common high-grade primary brain tumor, occurring primarily in adults. This infiltrating tumor locates deep in the white matter, subcortical structures and thalamus. The typical localization of glioblastoma is supratentorial, accounting for more than 99% of cases. Primary infratentorial growth of glioblastomas involving the cerebellum is a very rare condition, occurring in less than 1 % of cases reported in the literature. The differential diagnosis consists mainly of solitary metastatic lesions and medulloblastoma. The clinical manifestations of cerebellar lesions are similar, but the methods of surgical and chemoradiotherapy treatment, prognosis and outcome in cases with various histologic types of the tumors are different.Thus radiology, carried out using multiparametric MRI mapping, is an decision making procedure. In thus publication we present an atypical case of infratentorial glioblastoma in a 45-yearold patient.