Global Burden of Alzheimer’s Disease and Other Dementias Attributed to High Fasting Plasma Glucose from 1990 to 2019

Burden of Alzheimer’s disease (AD) and other dementias have grown rapidly over the decades, and high fasting plasma glucose (HFPG) was one of the well-established risk factors. It is urgently needed to estimate the global burden of AD and other dementias attributable to high fasting plasma glucose between regions, countries, age groups, and sexes to inform development of effective primary disease prevention strategies and intervention policies. The burden of AD and other dementias attributable to HFPG was estimated based on a modeling strategy using the Global Burden of Disease Study 2019 dataset. The disease burden and time trend globally and by region, country, development level, age group, and sex were evaluated. The number of AD and other dementias-related deaths attributable to HFPG increased from 42,998.23 (95