Coordinated ARP2/3 and Glycolytic Activities Regulate the Morphological and Functional Fitness of Human CD8+ T Cells

Anton Kamnev, Tanvi Mehta,Matthias Wielscher,Beatriz Chaves,Claire Lacouture,Anna-Katharina Mautner,Lisa E. Shaw,Michael Caldera,Joerg Menche,Wolfgang P. Weninger,Matthias Farlik,Kaan Boztug,Loic Dupre

CELL REPORTS（2024）

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Key words

cytotoxic T cells,adhesion,motility,immunological synapse,actin cytoskeleton,ARP2/3 complex,IL-2,glycolysis,OXPHOS,high-content cell imaging,RNA sequencing

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