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Single-nucleus RNA Sequencing Demonstrates an Autosomal Dominant Alzheimer's Disease Profile and Possible Mechanisms of Disease Protection.

Maria Camila Almeida, Sarah J. Eger, Caroline He,Morgane Audouard,Arina Nikitina,Stella M. K. Glasauer,Dasol Han, Barbara Mejia-Cupajita,Juliana Acosta-Uribe,Nelson David Villalba-Moreno,Jessica Lisa Littau, Megan Elcheikhali, Erica Keane Rivera,Daniel Carneiro Carrettiero,Carlos Andres Villegas-Lanau,Diego Sepulveda-Falla,Francisco Lopera,Kenneth S. Kosik

NEURON（2024）

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关键词
PSEN1-E280A,spatial transcriptomics,autophagy,chaperones,single-nucleus sequencing,APOE3 Christchurch,sporadic Alzheimer's disease,transcriptomics
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