Identification of Benzothiazole Derived Monosaccharides As Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3; a Rare Example of Using a S···O Binding Interaction for Drug Design.
BIOORGANIC & MEDICINAL CHEMISTRY（2024）
关键词
Galectin-3 (Gal-3),Galectin-3 (Gal-3) inhibitor,Monosaccharide galectin-3 (Gal-3) inhibitor,Benzothiazole,Interaction between sulfur and carbonyl oxygen atoms,X-ray co-crystal structure with Galectin-3 (Gal-3)
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