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Silencing Apoe with Divalent-Sirnas Improves Amyloid Burden and Activates Immune Response Pathways in Alzheimer's Disease.

Chantal M. Ferguson,Samuel Hildebrand,Bruno M. D. C. Godinho,Julianna Buchwald,Dimas Echeverria,Andrew Coles,Anastasia Grigorenko,Lorenc Vangjeli,Jacquelyn Sousa,Nicholas McHugh,Matthew Hassler,Francesco Santarelli,Michael T. Heneka,Evgeny Rogaev,Anastasia Khvorova

ALZHEIMERS & DEMENTIA（2024）

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关键词
Alzheimer's Disease,Apoe,neurodegeneration,oligonucleotide therapeutics,RNAi,siRNA
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