[Implementation of an Advanced Planning and Scheduling System in a Pharmaceutical Context].

Optimizing its supply chain has now become more than a necessity for any company seeking to expand its national and international market, so that it is able to continue its progress and fulfil its obligations towards its employees and its customers, particularly in the pharmaceutical context. The Covid-19 pandemic has shown the importance of resilience in the pharmaceutical industry to deal with unexpected disruptions and high demand from patients and authorities. Better production planning based on data management and predictive analysis, through the use of new Industry 4.0 tools, improves operational performance in terms of productivity and flexibility in relation to the vagaries of the request. It is in this vision that we approach the implementation of an "Advanced Planning and Scheduling-APS" system, in a pharmaceutical laboratory. It is a leading company in the Tunisian pharmaceutical market that seeks to expand its national and international market. In this work, we describe its project to implement an "Advanced Planning and Scheduling" system and its integration with its already functional "Enterprise Resource Planning" software system, as complementary decision-making tools. (c) 2024 Academie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.