Exploring the Impact of the PNPLA3 I148M Variant on Primary Human Hepatic Stellate Cells Using 3D Extracellular Matrix Models.

Elisabetta Caon,Maria Martins, Harry Hodgetts, Lieke Blanken,Maria Giovanna Vilia,Ana Levi,Kessarin Thanapirom,Walid Al-Akkad,Jeries Abu-Hanna,Guido Baselli,Andrew R. Hall,Tu Vinh Luong,Jan-Willem Taanman,Michele Vacca,Luca Valenti,Stefano Romeo,Giuseppe Mazza,Massimo Pinzani,Krista Rombouts

JOURNAL OF HEPATOLOGY（2024）

Cited 0|Views54

Key words

Hepatic stellate cells,PNPLA3,fibrosis,3-dimensional (3D) models,extracellular matrix (ECM),transcriptomics,mitochondrial dysfunction,oxidative stress,TGFB1

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