Synthesis of Α-Sulfenylated Carbonyl Compounds under Metal-Free Conditions
ORGANIC & BIOMOLECULAR CHEMISTRY(2024)
摘要
An efficient synthesis of alpha-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols under heating conditions is described. The method is characterized by mild conditions, simple operation, metal-free catalysis and good functional group tolerance. Mechanistic studies suggest that the reaction involves a radical pathway and an isomerization process. A highly efficient organocatalytic protocol for the synthesis of alpha-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols is established. A wide range of alpha-sulfenylated carbonyl compounds were obtained in moderate to good yields.
更多查看译文
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要