Evaluation of PD-1 and Interleukin-10-receptor Expression by T Lymphocytes in Malignant and Benign Pleural Effusions
Clinical and Experimental Medicine(2024)
摘要
PD-1 (programmed cell death protein-1)/PD-L1 (programmed cell death ligand 1) as well as IL-10 (interleukin-10)/IL-10R (interleukin-10 receptor) interactions play a major role in tumor immune evasion in various malignancies. Several studies investigated the expression of PD-1 on T lymphocytes in pleural effusions (PE) in patients with malignant diseases. However, results in malignant pleural effusions (MPE) compared to benign PE (BPE) are underreported. In this prospective study, 51 patients (median age 66 years, IQR 54–78, 47
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关键词
Pleural effusion,Programmed cell death protein 1,Interleukin-10 receptor,PD-1,IL-10R
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