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Peptide-scFv Antigen Recognition Domains Effectively Confer CAR T Cell Multiantigen Specificity

Jaquelyn T. Zoine,Kalyan Immadisetty,Jorge Ibanez-Vega,Sarah E. Moore,Chris Nevitt,Unmesha Thanekar,Liqing Tian, Abbas Karouni,Peter J. Chockley,Bright Arthur,Heather Sheppard,Jeffery M. Klco,Deanna M. Langfitt,Giedre Krenciute,Stephen Gottschalk,M. Madan Babu,M. Paulina Velasquez

Cell reports Medicine（2024）

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关键词
CAR T cell therapy,chimeric antigen receptor,immune escape,AML,leukemia,bispecific CAR,structure prediction,GRP78,CD123,B7H3
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