Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives
FRONTIERS IN MOLECULAR NEUROSCIENCE(2024)
摘要
Intracerebral hemorrhage (ICH) manifests precipitously and profoundly impairs the neurological function in patients who are affected. The etiology of subsequent injury post-ICH is multifaceted, characterized by the intricate interplay of various factors, rendering therapeutic interventions challenging. Astrocytes, a distinct class of glial cells, interact with neurons and microglia, and are implicated in a series of pathophysiological alterations following ICH. A comprehensive examination of the functions and mechanisms associated with astrocytic proteins may shed light on the role of astrocytes in ICH pathology and proffer innovative therapeutic avenues for ICH management.
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关键词
astrocytes,crosstalk,inflammatory response,intracerebral hemorrhage,neurological function
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